Bis 2 Chloroethyl Amine Hydrochloride

Product Description

Bis2chloroethylamine hydrochloride

Chemical Formula CHClN

Molecular Weight 19449 gmol

Overview

Bis2chloroethylamine hydrochloride is a chemical compound containing two chloroethyl functional groups attached to an amine It is a derivative of ethyleneimine and is structurally related to nitrogen mustards a class of alkylating agents

Structure

Contains a secondary amine NH bonded to two chloroethyl CHCHCl groups

The hydrochloride form makes it more stable and watersoluble

Reactivity

The chlorine atoms in the chloroethyl groups make it highly reactive

It can undergo alkylation reactions where it forms aziridinium ions which can react with nucleophilic sites in DNA or proteins

Applications

1 Precursor to Nitrogen Mustard Compounds

Used in the synthesis of mechlorethamine an early chemotherapy drug

Basis for other alkylating agents used in cancer treatment

2 Chemical Warfare Agents

Structurally related to mustard gas a vesicant blistering agent

3 Research Laboratory Use

Used in studies on DNA alkylation and cytotoxicity mechanisms

Toxicity Hazards

Highly toxic and mutagenic due to its ability to alkylate DNA

Can cause severe blistering and cellular damage

Carcinogenic and should be handled with extreme caution in a controlled lab setting