
3Carbamoylmethyl5Methylhexanoic Acid CMH
Chemical Overview
Molecular Formula CHNO
Molecular Weight 20126 gmol
Functional Groups
Carboxyl COOH
Amide CONH
Alkyl side chains
Structure and Properties
CMH contains a carbamoylmethyl CHCONH group attached to a 5methylhexanoic acid backbone It is structurally related to pregabalin a drug used for neurological conditions
Applications and Importance
1 Pharmaceutical Relevance
CMH is an intermediate in the synthesis of Pregabalin Lyrica an antiepileptic and neuropathic pain medication
May serve as a key building block for GABA analogs
2 Chemical and Biological Significance
Its structural similarity to neuroactive compounds suggests potential applications in drug development
Could be studied for effects on neurotransmitter modulation
Synthesis and Precursors
Derived from modifications of branchedchain fatty acids
Typically involves amide formation and carboxylation reactions
Toxicity and Safety
Likely low acute toxicity but safety data is limited
Should be handled with proper protective equipment in a lab setting
Would you like synthetic routes mechanisms of action or related compounds
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